Heartburn Meds May Lead to Bone Breaks Says New Study : RushPRNews - Newswire & Global Press Release Distribution

 
Bookmark and Share

Heartburn Meds May Lead to Bone Breaks Says New Study

June 4, 2009

NEW YORK (RPRN) 6/4/2009--Older patients may have to pass on the heartburn drugs to spare their bones from fractures according to a new study. According to a presentation at this year’s Digestive Disease Week 2009, even short-term use of popular acid-reducing heartburn drugs may raise the risk of hip fractures.

The increased risks appeared two years after patients started taking proton pump inhibitors such as Prevacid and histamine-2 receptor antagonists, or H2RAs, such as Zantac and Tagamet. Other proton pump inhibitors include popular brands such as Nexium, Prilosec, Protonix, and Aciphex.

The study suggests long-term use of proton pump inhibitors -- for at least five years -- may raise the risk of hip fractures.

Dr. Douglas Corley, who led the study, said in a statement, “The increased risk with short-term use of acid-suppressing drugs suggests that even relatively brief periods of use may be associated with increased risk of hip fractures.” Dr. Corley advises patients taking acid blockers to continue treatment at the lowest effective dose, but people at risk of osteoporosis should talk to their doctor about other treatment options.

For the study, Dr. Corley and colleagues analyzed data on nearly 40,000 patients taking acid-reducing drugs, and compared them to more than 130,000 patients not taking the drugs. People aged fifty to fifty-nine who had been on proton pump inhibitors for more than two years had the biggest increase in fracture risk with taking the drugs, they said.

The findings come as no surprise to bone expert Warren Levy, PhD, and CEO of Unigene Laboratories, who notes that there have been reports during the past few years suggesting that the use of certain proton pump inhibitors for more than five years to treat gastric reflux may be associated with increased fracture risk. Just last August, a Canadian study found that long-term use of proton pump inhibitors quadrupled the risk of a hip fractures.

“This new study suggests that such a link may begin earlier, even within two years. Some investigators have speculated previously that the association between PPI products and osteoporosis may result from poor absorption of calcium through the stomach,” says Dr. Levy.

According to Dr. Levy, since certain forms of calcium do not dissolve easily in the stomach, and acidic conditions can enhance the dissolution of calcium, it has been suggested that the reduction in stomach acid caused by PPI drugs may result in poor calcium absorption.

“Although more work needs to be done to confirm this finding, this study suggests that people with, or at risk for, osteoporosis should speak with their physicians regarding the use of PPI products even for shorter periods of time,” advises Dr. Levy, whose team is developing osteoporosis medications to prevent bone loss, promote bone growth and a surgical procedure, called Site-Directed Bone Growth (SDBG), that may help prevent and treat bone fractures. The SDBG technology, jointly invented in collaboration with Dr. Agnès Vignery at the Yale School of Medicine, is designed to facilitate and accelerate bone growth at precisely targeted locations in the body using a simple surgical procedure that can be performed on an outpatient basis with minimal invasiveness.

Janet Vasquez


Director, Corporate/ Financial Communications


---------------------------------------------


The Investor Relations Group


11 Stone Street


3rd Floor


New York, NY 10004


(212) 825-3210


(212) 825-3229 (fax)


jvasquez@investorrelationsgroup.com


www.irgnews.com


http://www.investorrelationsgroup.com


For more information, log onto http://irgnews.com/coi/UGNE.

About the author:

Janet Vasquez, Director of Corporate Communications

About IRG

We are The Investor Relations Group (IRG), a full-service corporate communications firm that provides investor relations and public relations services to nano-, micro- and small-cap companies providing them with the equivalent in-house services of a large-cap company.

http://www.investorrelationsgroup.com

Click here to see all news from this author/company

Filed Under: Health and Fitness, Lifestyle, YAHOO NEWS, FDA- Pharmaceutical news, SCIENCE, Article-byline

RUSH PR NEWS newswire and press release services at rushprnews.com / Anne Howard annehowardpublicist.com

Content- Legal Responsibility - All material is copyrighted - You may repost but you MUST link back to the original post on your page and acknowledge Rush PR News as the news source. Rush PR News is not legally and/or morally responsible for content of press releases, opinions expressed or fact-checking.

Rush PR News cannot be held legally responsible for material published and distributed through its newswire service or published in its press-room and therefore cannot be sued for published material. Third-party must be contacted directly to dispute content.

Rush PR News is not the contact for material published.

RSSFeed PRESS & SOCIAL MEDIA RELEASES

GreenRoad bolsters focus on North American market with new Austin, Texas headquarters and top level appointments

San Jose, CA 05/26/15 · GreenRoad Technologies, the leading provider of Software-as-a-Service (SaaS)...

Canadian Anchor Baffled: Most People in LA Don't Know Who Sinatra Was

Hollywood, CA 05/22/15 · A Manitoba.24 anchor, MIKE BANANA, has held a...

Nostra Products - New Chalkboard Decor

New York, NY 05/18/15 · Nostra Products introduces a new product! Chalkboard decor...

AirBnB of food has arrived to London

London, United Kingdom 05/13/15 · - TRYMYKITCHEN.COM  BRINGS UNIQUE FOOD CONCEPT TO LONDON...

They Tell Their Story at the 32nd Annual McDonald’s Gospelfest and Competition

Newark, New Jersey 05/13/15 · Star-Studded Event at The Prudential Center, Newark New...

Newly Renovated Running Aces Casino & Racetrack to Host Preakness Event on May 16th

COLUMBUS, MN 05/12/15 · “The Triple Crown is a celebrated American tradition,...

Raleigh IT Business Celebrates 20 Years Of Serving Businesses Across North Carolina

Raleigh, NC 05/04/15 · CSP Extends Our Appreciation to Those Who Joined...

AK for Real Estate Development & Marketing to Settle with Egyptian Government

Cairo, Egypt 04/30/15 · Egyptian developer AK for Real Estate Development &...

Aspect/Bruker 3-year partnership concluded in March 2015

SHOHAM, Israel 04/26/15 · A world leader in ground-breaking, compact benchtop MRI...

IT Secure Services Expands Business Operations Into Massachusetts

Manchester, NH 04/23/15 · Businesses In The 128 Tech Corridor Finally Have...

ASTEP Announces Cindy Gentry, Senior Partner at Mercer U.S., as New Advisory Board Member

NEW YORK, NY 04/21/15 · The Asperger Syndrome Training and Employment Partnership (ASTEP)...

500 BC Introduces YouQuest App. Update Your Life, Not Your Status.

Washington, DC 04/21/15 · Harnessing ancient wisdom to meet modern challenges. “Update...