To Heal Diabetic Foot Ulcers, A New Drug Harnesses Stem Cells Inside Us All : RushPRNews - Newswire & Global Press Release Distribution

 
Bookmark and Share

To Heal Diabetic Foot Ulcers, A New Drug Harnesses Stem Cells Inside Us All

November 12, 2009

Princeton, NJ (RPRN) 11/12/09 — Diabetic foot ulcers are the primary cause of hospital admissions for diabetics. Foot ulcers that heal improperly are at risk for infection, which can lead to amputation.  According to the American Diabetes Association, one in four patients with diabetic foot ulcers will eventually require lower-limb amputation.  Now science has found a way of mobilizing stem cells within the body to treat this health issue, which affects more than three million Americans annually.

Mesenchymal stem cells (MSCs), as distinct from the embryonic type, may be the key to healing diabetic foot ulcers.  These stem cells can differentiate into various cell types.  As a fetus develops, MSCs help drive its rapid initial growth; by the time we reach our teens, however, MSCs are mostly found in bone marrow.  

When wounded or burned, our skin craves MSCs, which it harbored when first growing.  In fact, recent studies show that surgically moving these cells from bone marrow onto hard-to-heal wounds accelerates healing.  

In contrast to surgically removing MSCs from bone marrow—a painful, time consuming and expensive process—a new topical drug, the novel angiotensin analog DSC127, appears to activate the mesenchymal stem cells in a patient’s body. 

“It appears that DSC127 directs MSCs to the injury site, mobilizing them to help repair wounded or burned skin, accelerate healing and reduce scar formation,” said Edward J. Quilty, Chairman & CEO of Derma Sciences Inc.  Based in Princeton, New Jersey, Derma Sciences develops, manufactures, and markets innovative wound care products.  “DSC127,” Quilty observed, “thus works as a catalyst for a stem cell treatment that is free of both the ethical controversies surrounding the medical use of fertilized embryos as well as potentially painful surgical interventions.”

Currently in a 75-patient Phase II diabetic foot ulcer clinical trial being conducted at some of the nation’s top institutions, the drug is being considered for additional indications including venous leg ulcers, arterial ulcers, pressure ulcers, thermal and chemical wounds, and scar prevention.  Pre-clinical animal studies have demonstrated the efficacy of the compound in accelerating healing and reducing scar formation. 

If DSC127 is approved for market, patients with diabetic foot ulcers may find a solution already exists within their own bodies.  For more information, visit www.dermasciences.com.

Media Contact Name: Janet Vasquez
Media E-mail: moc.puorgsnoitalerrotsevni@zeuqsavj
Media Phone: 212-825-3210
Media Web Address: http://www.irgnews.com
Company Web Address: http://www.dermasciences.com
About the author:

Janet Vasquez, Director of Corporate Communications

About IRG

We are The Investor Relations Group (IRG), a full-service corporate communications firm that provides investor relations and public relations services to nano-, micro- and small-cap companies providing them with the equivalent in-house services of a large-cap company.

http://www.investorrelationsgroup.com

Click here to see all news from this author/company

Filed Under: Article-byline, BREAKING NEWS, FDA- Pharmaceutical news

RUSH PR NEWS newswire and press release services at rushprnews.com / Anne Howard annehowardpublicist.com

Content- Legal Responsibility - All material is copyrighted - You may repost but you MUST link back to the original post on your page and acknowledge Rush PR News as the news source. Rush PR News is not legally and/or morally responsible for content of press releases, opinions expressed or fact-checking.

Rush PR News cannot be held legally responsible for material published and distributed through its newswire service or published in its press-room and therefore cannot be sued for published material. Third-party must be contacted directly to dispute content.

Rush PR News is not the contact for material published.

RSSFeed PRESS & SOCIAL MEDIA RELEASES

Renew Life’s #MomentsOfJoy Campaign Gaining Momentum On Social Media

Milton, ON 03/26/15 · Supplement Co. Recognizing Canadians Making Positive Impact On...

1.5 Million Website Visitors plus Ad impressions

Santa Cruz, California 03/21/15 · Mobile and responsive web traffic The banner will also...

Celebrity wedding planner Linda Galloway hired for UK socialite wedding in 2016

Notting Hill, London, UK 03/21/15 · Celebrity wedding planner, Linda Galloway of New York,...

iExpertsForum introduces SEOProfiler to its Top 5 SEO Tools

US 03/21/15 · iExpertsForum have now included an all new and...

Aspect/Bruker 3-year partnership concludes at the end of March 2015

SHOHAM, Israel 03/21/15 · A world leader in ground-breaking, compact benchtop MRI...

Pure HCG Diet Drops Offer Premium Quality HCG Triumph

St.Louis, Missiouri 03/21/15 · Weight gain is now offering major problems among...

Identify genuine web traffic from bots and botnets

SAN FRANCISCO 03/21/15 · As a provider of high-quality web traffic, Traffic...

Strike Up Your Website Traffic With Traffic Striker

Los Angeles, CA 03/21/15 · Every Website Needs Traffic To Succeed. Kick start...

Alzheimer's breakthrough using ultrasound

AUSTRALIA 03/18/15 · A new way of treating Alzheimer's disease with...

Ultraseal International boosts its international sales team

Coventry, UK 03/13/15 · Ultraseal International, a global leader in finding solutions...

Warwick Analytics launches first commercial Automated Information Retrieval system

LONDON 03/12/15 · Predictive Analytics specialists Warwick Analytics, has released the...

Steve Nash Fitness Clubs Celebrates new Burnaby location with Grand Opening Event

Vancouver, BC 03/09/15 · Steve Nash Fitness Clubs launches a new state...

Ultraseal International wins Exporter of the Year for second time running

Coventry, UK 03/06/15 · Ultraseal International has scooped Exporter of the Year...