Recombinetics Uses NIH Grant and Pigs to Advance War on Atherosclerosis and Heart Disease : RushPRNews - Newswire & Global Press Release Distribution

 
Bookmark and Share

Recombinetics Uses NIH Grant and Pigs to Advance War on Atherosclerosis and Heart Disease

January 17, 2013

Recombinetics Uses NIH Grant and Pigs to Advance War on Atherosclerosis and Heart Disease
Recombinetics

St. Paul, MN (rushPRnews) 01/17/13 — Little more than one year after receiving a $318,000 grant from the National Institutes of Health Heart, Lung and Blood Institute (NHLBI) to employ genetically modified pigs in the battle against atherosclerosis (hardening of the arteries) and heart disease, St. Paul, MN-based Recombinetics is taking the next big step. 

The company, which uses innovative gene editing and gene repair technologies to provide cutting edge research tools to scientists who study persistent human health risks, will soon deliver the first set of pigs to academic collaborators to fully characterize progression of the disease. Recombinetics used a line of Ossabaw pigs licensed from Indiana University-Purdue University Indianapolis that are genetically predisposed to develop Metabolic Syndrome, a collection of factors associated with coronary artery disease, stroke and Type II diabetes. Humans who suffer from Metabolic Syndrome are likely to develop these same diseases, which affect about 100 million Americans every year at a cost of over $400 billion. 

Recombinetics used its proprietary technologies to rapidly develop atherosclerosis in pigs – almost exactly as the human heart might do. The modified pigs will rapidly and consistently mimic the human version of atherosclerosis and its progression, making them invaluable to researchers studying new ways to prevent and treat this and other conditions leading to heart disease, America’s number one killer.

Recombinetics’ collaborators will carefully monitor the pigs using telemetry and high resolution imaging, and will chart the time course and pathology of disease onset and severity of atherosclerosis. Once the process is complete, animals will be available to research facilities in small numbers within the first months of 2014, according to Scott Fahrenkrug, Recombinetics CEO and Chairman.

“Until now, large animal models that predictably and consistently develop hardening of the arteries and heart disease have not been available to researchers working to prevent and treat these diseases. Using this NIH grant, we have utilized our own gene editing technology to produce pigs that will certainly speed, and could well revolutionize research into a family of diseases that kill hundreds of thousands of Americans every year and millions worldwide.”

The animals will be Recombinetics’ first commercial product, explained Fahrenkrug. Recombinetics is currently seeking private investors in support of its continued development and growth and was recently issued three landmark patents for gene editing and gene repair technology. The company also holds a global, exclusive license from Cellectis Bioresearch for application of homing endonucleases to livestock for biomedicine and animal agriculture.

ABOUT RECOMBINETICS

Founded in 2008, Recombinetics, Inc. is a global innovator in proprietary precision gene repair and gene editing technology. Breakthrough scientific research - including the development of TALEN technologies- has resulted in global exclusive rights in the biomedical, animal agriculture and livestock vertical markets. Recombinetics has garnered both private sector funding and significant development contracts from the National Institutes of Health, the US Department of Agriculture and the global commercial leaders in livestock genetics.

Media Contact Name: Annamarie Saarinen
Media Phone: (612) 964-6728
Click here to see all news from this author/company

Filed Under: BREAKING NEWS, Technology, PRESS RELEASE

RUSH PR NEWS newswire and press release services at rushprnews.com / AH Marketing ahmarketinggroup.com

Content- Legal Responsibility - All material is copyrighted - You may repost but you MUST link back to the original post on your page and acknowledge Rush PR News as the news source. Rush PR News is not legally and/or morally responsible for content of press releases, opinions expressed or fact-checking.

Rush PR News cannot be held legally responsible for material published and distributed through its newswire service or published in its press-room and therefore cannot be sued for published material. Third-party must be contacted directly to dispute content.

Rush PR News is not the contact for material published.

RSSFeed PRESS & SOCIAL MEDIA RELEASES

Heero: the Perfect 3D Printing Partner Monitors & Controls Progress

Brisbane, Australia 07/21/16 · Heero: Aussie Design Team Launches Kickstarter for Device...

Wharton MBA Students to Release World’s First Consumer Smart-Mirror

NEW YORK 07/20/16 · A team of Wharton MBA students announced that...

Gallery Pouch Protects your Artwork During Shipping

Dallas, Texas 07/14/16 · Great protective packaging when shipping all delicate objects...

SAP Shows Further Commitment to the SME Market by Hiring New President

London, UK 07/14/16 · If, when you think about SAP SE's main...

What Credit Market Experts Are Saying about Brexit

London, UK 07/08/16 · In the initial hours after the leave vote...

Why Starting Off with VPS Hosting is a Wise Decision

London, UK 06/27/16 · You may have heard the term ‘VPS Hosting,...

FlipBelt Launches Hydration Belt for Runners and Fitness Enthusiasts

DENVER, CO 06/22/16 · FlipBelt announces new version of its wildly popular...

Kickstarter Fun: Wu & Y: Combines Art & Activewear

Brooklyn, NY 06/16/16 · Artistic Activewear Brand Raises 20K on the First...

Nursing Schools Struggle to Keep Up With Demand for Nurses

Peoria, Illinois 06/15/16 · Recent studies carried out by the Georgetown Center...

20 Dollars Discount On All PR Distribution Packages Now

San Francisco 06/14/16 · Time to share the joy again! We just...

A Look Back at RPRNmag Newsmagazine Crowdfunding Stories

San Francisco 06/09/16 · CROWDFUNDING A Look Back at Crowdfunding Campaigns: From Wood...